Tetrapeptide-21 activates collagen production and decreases volume of wrinkles and fine lines | MaxLife News

Johnny Yu

Tetrapeptide-21 as Anti-Aging Agent 

Peptides are amino acids that make up the proteins in the skin. They have same chemical structure as proteins. They become proteins when they form a long chain of amino acids. However, when peptides are in a short chain of amino acids, they have the ability to penetrate the upper layer of the skin and signal the cells to tell them how to function. In cosmetic ingredients lists you might have seen tri-peptides, for example, or di-peptide. These different names refer to the number of amino acids. A di-peptide has two amino acids, tri-peptide has three amino acids and a tetra-peptide has four amino acids. And so on. 

Tetrapeptide is a synthetic peptide comprised of four amino acids, are active molecules that send signals to your cells. Now a day’s Tetrapeptides are common ingredients in skin anti-aging products. Although skin contains an abundance of collagen, the supply decreases with age, which is why there begins to appear fine lines and wrinkles. 

Activating collagen production 
Synthetic Tetrapeptide-21 have shown promise as a skin cream ingredient that can stimulate skin growth and repair. When collagen breaks down, it forms specific Tetrapeptides that signal to your skin that it was damaged and needs to make new collagen. So by applying Tetrapeptides topically, we are trying to trick our skin into thinking that it has lost collagen recently and needs to make more. It activates collagen production and therefore stimulates dermal filling, repair and renewal mechanisms of the skin. In short making skin to work as it was young and helping improve its look. 

There are lots of different synthetic Tetrapeptides available in anti-aging skincare products and they have many roles. One of the most important one is Tetrapeptide-21. 

Tetrapeptide-21 is a type of synthetic peptide compound which combines several chains of amino acids, which lead to an increased elasticity and a decreased volume of wrinkles and fine lines. Formulations containing 5% Tetrapeptide-21 have shown a 25% improvement in skin roughness and depth of fine and coarse wrinkles. 

It also increases the amount of secreted collagen protein in the supernatant of human dermal fibroblast cultures and furthermore enhances the gene expression of important ECM proteins like collagen I and fibronectin and stimulates hyaluronic acid production. 

Cell communicating peptide 
Tetrapeptide-21 is a cell communicating peptide that prevents damage caused by UV radiation. Moreover, it promotes DNA repair, to provide a complete protection system against intrinsic and extrinsic aging. 

Now a days’ tetrapeptide-21 is part of most of the high profile skin care products that help to produce more collagen. As you age, you lose collagen in your face making your skin get loose and saggy. By using these special skin care lines, your body will increase collagen production to give you naturally plump, tight skin and making the skin more youthful and glowing. 


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